Extraction of lobetyolin from codonopsis with supercritical CO2 / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 560-563, 2009.
Artículo
en Chino
| WPRIM
| ID: wpr-265383
ABSTRACT
<p><b>OBJECTIVE</b>To develop a green and rapid method for extraction of lobetyolin from C. pilosula.</p><p><b>METHOD</b>Extraction of lobetyolin from C. pilosula with supercritical carbon dioxide in the presence of ethanol was studied. The effects of pressure, temperature, volume of cosolvent and extraction time on efficiency and their interactive relationships were discussed, based on central composite design and response surface methodology (RSM).</p><p><b>RESULT</b>The key effect factor was volume of cosolvent. The extraction yield of lobetyolin was 0.078 6 mg x g(-1) when C. pilosula (40-60 mesh) was extracted at 30 MPa, 60 degrees C and 2 L x min(-1) (as CO2 in normal pressure and temperature) for 100 minutes with supercritical CO2 and 1 mL x min(-1) ethanol as dynamic cosolvent.</p><p><b>CONCLUSION</b>This result is better than that obtained from traditional method. Therefore, the optimized process is valuable for extraction of lobetyolin from C. pilosula.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Dióxido de Carbono
/
Medicamentos Herbarios Chinos
/
Química
/
Codonopsis
/
Etanol
/
Fraccionamiento Químico
/
Polímero Poliacetilénico
/
Métodos
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2009
Tipo del documento:
Artículo
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