A meta-analysis of clinical outcomes after laparoscopic operation for rectal cancer / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 831-835, 2010.
Artículo
en Chino
| WPRIM
| ID: wpr-266263
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the clinical outcomes after laparoscopic surgery for rectal cancer.</p><p><b>METHODS</b>A systematic literature search (Medline, Embase, Cochrane Library) as of March 2010 was performed to identify all eligible studies. Two reviewers independently screened and extracted the data. Differences in short-term and long-term clinical outcomes after laparoscopic resection (LR) and open resection (OR) were analyzed using RevMan 5.</p><p><b>RESULTS</b>A total of 1042 abstracts were retrieved and 16 clinical controlled studies finally included. The total number of patients was 2850. There were 1145 patients received LR and 1705 received OR. The analyses showed that LR had longer operative time (WMD=42.50, 95%CI 29.27 to 55.74, P<0.05), less harvested lymph nodes (WMD=-0.94, 95%CI -1.47 to -0.41, P<0.05), and less blood loss (WMD=-158.46, 95%CI -221.08 to -95.84, P<0.05) as compared to OR. LR was superior to OR in terms of surgical mortality (OR=0.40, 95%CI 0.18 to 0.92, P=0.03), postoperative complications (OR=0.73, 95%CI 0.61 to 0.87, P<0.05), and 5-year overall survival rate (OR=1.56, 95%CI 1.21 to 2.02, P<0.05). There was no significant difference in positive rate of circumferential resection margin between the two groups (OR=1.00, 95%CI 0.45 to 2.20, P=1.00).</p><p><b>CONCLUSION</b>Compared to open surgery, short-term and long-term clinical outcomes after laparoscopic surgery are favorable.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Neoplasias del Recto
/
Cirugía General
/
Resultado del Tratamiento
/
Laparoscopía
/
Ensayos Clínicos Controlados como Asunto
Tipo de estudio:
Ensayo Clínico Controlado
/
Revisiones Sistemáticas Evaluadas
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Gastrointestinal Surgery
Año:
2010
Tipo del documento:
Artículo
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