Effect of SS8, the active part of Spatholobus suberectus Dunn, on proliferation of hematopoietic progenitor cells in mice with bone marrow depression / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 152-155, 2003.
Artículo
en Chino
| WPRIM
| ID: wpr-266795
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect of SS8, a monomer extracted from Spatholobus suberectus Dunn used for invigorating the circulation of blood, on proliferation of hematopoietic progenitor cells in mice with bone marrow depression.</p><p><b>METHOD</b>The method of semi-solid culture with methylcellulose of CFU-GM, CFU-E, BFU-E, CFU-Meg was adopted in bone marrow depressed mice which were treated with SS8 for a long time.</p><p><b>RESULT</b>The experimental data demonstrated that the numbers of CFU-GM, CFU-E, BFU-E, CFU-Meg in bone marrow depressed mice were raised distinctly under the control of SS8 as compared with those of contrast group. The effect of SS8 became stronger as time went on and the dosage rose.</p><p><b>CONCLUSION</b>SS8 can distinctly stimulate the proliferation of hematopoietec progenitor cells in mice with bone marrow depression in a time-and-dosagedependent manner.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Plantas Medicinales
/
Efectos de la Radiación
/
Células de la Médula Ósea
/
Células Madre Hematopoyéticas
/
Medicamentos Herbarios Chinos
/
Células Precursoras Eritroides
/
División Celular
/
Química
/
Irradiación Corporal Total
Límite:
Animales
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2003
Tipo del documento:
Artículo
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