Epstein-Barr Virus Associated Hemophagocytic Syndrome after Scrub Typhus Infection / 감염과화학요법
Infection and Chemotherapy
;
: 330-333, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-26684
ABSTRACT
There have been a small number of cases of scrub typhus-associated hemophagocytic syndrome (HPS), most of which were treated successfully using adequate antibiotics. Here, we report a case of Epstein-Barr virus (EBV)-associated HPS after scrub typhus infection that was not improved using antirickettsial treatment. A 73-year-old male who had been diagnosed with scrub typhus according to an eschar and a positive serology was transferred to our institution because of a persistent fever despite 7-day doxycycline therapy. Physical and laboratory data showed hepatosplenomegaly, bicytopenia, hyperferritinemia, and hypofibrinogenemia. A bone marrow examination (BM) revealed hypercellular marrow with hemophagocytosis and histiocyte infiltration. EBV was detected in BM aspirates using polymerase chain reaction. After a diagnosis of HPS was made, the patient was treated successfully using high-dose steroids.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Esteroides
/
Médula Ósea
/
Examen de la Médula Ósea
/
Tifus por Ácaros
/
Reacción en Cadena de la Polimerasa
/
Doxiciclina
/
Herpesvirus Humano 4
/
Infecciones por Virus de Epstein-Barr
/
Diagnóstico
/
Linfohistiocitosis Hemofagocítica
Tipo de estudio:
Estudio diagnóstico
Límite:
Anciano
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Infection and Chemotherapy
Año:
2016
Tipo del documento:
Artículo
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