Chemical constituents of Phymatopteris hastate and their antioxidant activity / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1402-1407, 2012.
Article
en Zh
| WPRIM
| ID: wpr-267008
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ABSTRACT
<p><b>OBJECTIVE</b>To study chemical constituents contained in Phymatopteris hastate and their antioxidant activity.</p><p><b>METHOD</b>Chemical constituents were separated and purified from P. hastate by using such methods as silica gel, Toyopearl HW-40C and HPLC preparative chromatography. Their structures were identified by spectroscopic methods such as NMR. Furthermore, 1, 1-diphenyl-2-picryl-hydrazyl(DPPH) method was used to assess the antioxidant activity of each compound.</p><p><b>RESULT</b>Fourteen compounds were separated and identified as 4-O-beta-D-glucopyranosyl-ethyl-trans-caffeicate (1), kaempferlo-7-O-alpha-L-rhamnopyranside (2), kaempferol-3, 7-di-O-alpha-L-rhamnopyranoside (3), kaempferol-3-O-alpha-L-arabinofuranosyl-7-O-alpha-L-rhamnopyranoside (4), juglanin (5), naringin (6), naringenin-7-O-beta-D-glucopyranoside (7), trans-caffeic acid (8), trans-caffeic acid-3-O-beta-D-glucopyranoside (9), trans-cinnamic acid-4-O-beta-D- glucopyranoside (10), trans-melilotoside (11), cis-melilotoside (12), ethyl chlorogenate (13), protocatechuic acid (14). The antioxidation experiment showed an obvious antioxidant activity in compounds 1-9, 13-14.</p><p><b>CONCLUSION</b>All of the compounds were separated from this genus for the first time. Among them, compound 1 was not seen in literature reports and assumed to be a new artifact derived from compound 9 and ethanol. Compounds 1-9, 13-14 showed a remarkable antioxidant activity.</p>
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Asunto principal:
Farmacología
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Medicamentos Herbarios Chinos
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Espectroscopía de Resonancia Magnética
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Cromatografía Líquida de Alta Presión
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Flavanonas
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Quempferoles
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Antioxidantes
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2012
Tipo del documento:
Article