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Management and prognostic factors for 119 patients with follicular thyroid carcinoma / 中华肿瘤杂志
Chinese Journal of Oncology ; (12): 778-782, 2013.
Artículo en Chino | WPRIM | ID: wpr-267457
ABSTRACT
<p><b>OBJECTIVE</b>To explore the optimal management and analyze the prognostic factors for follicular thyroid carcinoma.</p><p><b>METHODS</b>The clinicopathological data of 119 patients with well-differentiated follicular thyroid carcinoma treated in our hospital from 1970 to 2008 were retrospectively reviewed. The overall survival (OS) rate was estimated by Kaplan-Meier method. Log rank and Cox regression analyses were used to identify the prognostic factors.</p><p><b>RESULTS</b>The 5- and 10-year OS rates were 81.1% and 66.7%, respectively. The 3- , 5- and 10-year cumulative distant metastasis rates were 27.4%, 29.6% and 35.9%, respectively. The age of ≥ 45 years old was one of the most important factors affecting survival rate (P < 0.05) and an independent factor for distant matastasis.</p><p><b>CONCLUSIONS</b>Follicular thyroid carcinoma has some special features such as diffuse growth and vascular tumors thrombosis and with a relatively poor prognosis. The key measure to improve local control and prognosis is radical resection. Some aggressive management such as total thyroidectomy combined with (13)1I therapy and regular follow-up should be performed to improve the survival rate and to control postoperative distant metastasis for patients ≥ 45 years old.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Patología / Radioterapia / Cirugía General / Tiroidectomía / Neoplasias Óseas / Neoplasias de la Tiroides / Tasa de Supervivencia / Estudios Retrospectivos / Estudios de Seguimiento / Factores de Edad Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Adolescente / Adulto / Anciano / Aged80 / Niño / Femenino / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Oncology Año: 2013 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Patología / Radioterapia / Cirugía General / Tiroidectomía / Neoplasias Óseas / Neoplasias de la Tiroides / Tasa de Supervivencia / Estudios Retrospectivos / Estudios de Seguimiento / Factores de Edad Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Adolescente / Adulto / Anciano / Aged80 / Niño / Femenino / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Oncology Año: 2013 Tipo del documento: Artículo