IL-8 and TNF-alpha in prostatic secretions as indications in evaluating chronic prostatitis / 中华男科学杂志
National Journal of Andrology
;
(12): 740-742, 2004.
Artículo
en Chino
| WPRIM
| ID: wpr-267824
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the significance of the determination of IL-8 and TNF-alpha in prostatic secretions in the evaluation of chronic prostatitis.</p><p><b>METHODS</b>IL-8 and TNF-alpha levels in EPS were evaluated by ELISA in 90 men controls (n = 12), CBP (n = 12), CPPS IIIA (n=38), CPPS IIIB (n=28). And the difference was analyzed between CBP or CPPS IIIA and CPPS IIIB or controls.</p><p><b>RESULTS</b>IL-8 and TNF-alpha levels in EPS were higher in men with CBP [(10967.5 +/- 3477.7) pg/ml, (84.1 +/- 54.7) pg/ml] or CPPS IIIA [(9268.4 +/- 2034.6) pg/ml and (32.6 +/- 18.6) pg/ml], but lower in men with CPPS IIIB [(2726.1 +/- 277.5) pg/ml, (12.6 +/- 7.1) pg/ml] or controls [(2800.0 +/- 320.2) pg/ml and (12.9 +/- 10.1) pg/ml] respectively. There was significant difference between CBP or CPPS IIIA and CPPS IIIB or controls (P < 0.01).</p><p><b>CONCLUSION</b>IL-8 and TNF-alpha are elevated in the EPS of the men with CBP and CPPS IIIA, and provide a novel means for the identification and characterization of chronic nonbacterial prostatitis/chronic pelvic pain syndrome. The cut-points for IL-8 and TNF-alpha to discriminate CBP or CPPS IIIA from CPPS IIIB or controls need further investigation.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Prostatitis
/
Líquidos Corporales
/
Ensayo de Inmunoadsorción Enzimática
/
Estudios de Casos y Controles
/
Química
/
Enfermedad Crónica
/
Interleucina-8
/
Factor de Necrosis Tumoral alfa
/
Secreciones Corporales
/
Diagnóstico
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
Límite:
Adulto
/
Anciano
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
National Journal of Andrology
Año:
2004
Tipo del documento:
Artículo
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