Synthesis and biological activity of a series of benzopyran derivatives / 药学学报
Acta Pharmaceutica Sinica
; (12): 162-168, 2008.
Article
en Zh
| WPRIM
| ID: wpr-268152
Biblioteca responsable:
WPRO
ABSTRACT
Thirteen benzopyran derivatives were synthesized and their activity stimulating the differentiation of preadipocytes into adipocytes were evaluated with 3T3-L1 cells. Compound 8 was also tested for its hypoglycemic activity on db diabetes mice model. Results indicated that compounds 3, 8 and 11 exhibited strong differentiation-stimulating activity on 3T3-L1 cells model, and compound 8 can reduce the blood-sugar level of db diabetes mice dramatically.
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Farmacología
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Benzopiranos
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Sangre
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Glucemia
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Diferenciación Celular
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Química
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Adipocitos
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Células 3T3-L1
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Diabetes Mellitus Experimental
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Hipoglucemiantes
Límite:
Animals
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Año:
2008
Tipo del documento:
Article