Biology of thioredoxin and its association with Alzheimer's disease and Parkinson's disease / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1-8, 2008.
Artículo
en Chino
| WPRIM
| ID: wpr-268181
ABSTRACT
Thioredoxin (Trx) is a crucial protein for antioxidative defense, as well as a redox regulator of the intra- and extracellular signaling pathways and transcription factors. In this review, we focus on mammalian Trx and its association with Alzheimer's disease (AD) and Parkinson's disease (PD). Based on the evidence of neuroprotective effects of Trx, up-regulation of Trx may be a good strategy for prevention and treatment of AD and PD.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Oxidación-Reducción
/
Enfermedad de Parkinson
/
Fisiología
/
Tiorredoxinas
/
Apoptosis
/
Fármacos Neuroprotectores
/
Enfermedad de Alzheimer
/
Metabolismo
/
Antioxidantes
Límite:
Animales
/
Humanos
Idioma:
Chino
Revista:
Acta Pharmaceutica Sinica
Año:
2008
Tipo del documento:
Artículo
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