Recent advances in the study of synthesis and activity of vancomycin derivatives / 药学学报
Acta Pharmaceutica Sinica
;
(12): 463-469, 2007.
Artículo
en Chino
| WPRIM
| ID: wpr-268616
ABSTRACT
Vancomycin was enlisted as a drug of the last resort for the treatment of resistant gram-positive bacterial infections. However, the emergence of vancomycin-resistant bacteria has created an urgent need for new active analogues of vancomycin. Summing up the last ten years work of this field, the review introduced the antibiotic mechanism of vancomycin and summarized the vancomycin derivatives based on the modifications of vancomycin, dimmer of vancomycin and the vancomycin mimetics. The connection of modified location and function with antibacterial activity was also discussed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Vancomicina
/
Estructura Molecular
/
Pruebas de Sensibilidad Microbiana
/
Química
/
Resistencia a la Vancomicina
/
Antibacterianos
Idioma:
Chino
Revista:
Acta Pharmaceutica Sinica
Año:
2007
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS