CA 125 expression in cervical and vaginal secretions in women in normal reproductive period / 南方医科大学学报
Journal of Southern Medical University
;
(12): 173-175, 2010.
Artículo
en Chino
| WPRIM
| ID: wpr-269597
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the tumor-associated antigen CA125 expression in the serum and cervical and vaginal secretions in women during normal reproductive period, and explore the clinical value of detecting tumor markers in the cervical and vaginal secretions.</p><p><b>METHODS</b>A total of 145 women in reproductive period were divided into 3 age groups (20-29 years, 30-39 years, and over 40 years), and their CA125 levels in cervical secretion, vaginal secretion and serum were detected by automatic electro-chemiluminescent immunoassay.</p><p><b>RESULTS</b>CA125 levels in the cervical secretion, vaginal secretion and serum showed no significant difference between the 3 age groups (P>0.05). In each group, CA125 levels differed significantly between the cervical secretion, vaginal secretion and serum (P<0.001). In the 145 women, the average CA125 level was 497.82 - or + 75.29 U/ml in the cervical secretion, 114.66 - or + 26.40 U/ml in vaginal secretion and 18.06 - or + 3.35 U/ml in serum, showing significant differences between them (P<0.001).</p><p><b>CONCLUSION</b>CA125 expression level is significantly higher in the cervical and vaginal secretions than in the serum in women in normal reproductive period, and its levels in cervical and vaginal secretions can be more sensitive and convenient for early detection of related diseases.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Vagina
/
Sangre
/
Biomarcadores
/
Moco del Cuello Uterino
/
Antígeno Ca-125
/
Secreciones Corporales
/
Metabolismo
Tipo de estudio:
Estudio de tamizaje
Límite:
Adulto
/
Femenino
/
Humanos
Idioma:
Chino
Revista:
Journal of Southern Medical University
Año:
2010
Tipo del documento:
Artículo
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