Autonomic and cardiovascular effects of pentobarbital anesthesia during trigeminal stimulation in cats / 国际口腔科学杂志·英文版
International Journal of Oral Science
;
(4): 24-29, 2012.
Artículo
en Inglés
| WPRIM
| ID: wpr-269648
ABSTRACT
Stimulation of the trigeminal nerve can elicit various cardiovascular and autonomic responses; however, the effects of anesthesia with pentobarbital sodium on these responses are unclear. Pentobarbital sodium was infused intravenously at a nominal rate and the lingual nerve was electrically stimulated at each infusion rate. Increases in systolic blood pressure (SBP) and heart rate (HR) were evoked by lingual nerve stimulation at an infusion rate between 5 and 7 mg·kg(-1)·h(-1). This response was associated with an increase in the low-frequency band of SBP variability (SBP-LF). As the infusion rate increased to 10 mg·kg(-1)·h(-1) or more, decreases in SBP and HR were observed. This response was associated with the reduction of SBP-LF. In conclusion, lingual nerve stimulation has both sympathomimetic and sympathoinhibitory effects, depending on the depth of pentobarbital anesthesia. The reaction pattern seems to be closely related to the autonomic balance produced by pentobarbital anesthesia.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Fentolamina
/
Fisiología
/
Sistema Nervioso Autónomo
/
Nervio Trigémino
/
Infusiones Intravenosas
/
Antagonistas Adrenérgicos alfa
/
Hexametonio
/
Relación Dosis-Respuesta a Droga
/
Estimulación Eléctrica
Límite:
Animales
Idioma:
Inglés
Revista:
International Journal of Oral Science
Año:
2012
Tipo del documento:
Artículo
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