Manganese neurotoxic effect and its susceptibility biomarkers of choice / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 856-859, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-269960
ABSTRACT
Long-term occupational exposure to manganese might cause manganese poisoning, which would had adverse effects on nervous system of workers. The basal nucleus was damaged and dopaminergic neuron was injuried by manganese. The mechanism could be related with interfering the energy metabolism of central nerve, changing neurotransmitters, activating oxidation system and so on. Genetic factors may also plays a significant role in the neurotoxicity caused by manganese. Study the effects of manganese exposure biomarker, the neurotoxicity of biomarkers and the genetic susceptibility to early and susceptibility biomarkers will contribute to the prevention and control of manganese neurotoxicity.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Biomarcadores
/
Exposición Profesional
/
Síndromes de Neurotoxicidad
/
Intoxicación por Manganeso
/
Susceptibilidad a Enfermedades
/
Manganeso
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Preventive Medicine
Año:
2015
Tipo del documento:
Artículo
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