Viral load test conducive to excluding negative subjects from suspects in HIV antibody detections / 中华预防医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study whether plasma viral load testing is helpful to exclude ones free from Human immunodeficiency virus (HIV) infections from suspects in HIV antibody detections.</p><p><b>METHODS</b>19 Specimens, which showed disconcordant results of the two HIV EIA testing (S/CO < 6) and indeterminated results of Western blot (WB) test, were selected. Viral load of the specimens were detected. A six-month follow up survey in detecting HIV antibody was conducted in these subjects.</p><p><b>RESULTS</b>None of these 19 cases was observed to be positive HIV viral loads and there was no any progress in WB bands development during the follow-up period. The possibility of HIV infection could be excluded.</p><p><b>CONCLUSION</b>When the specimens react with very low intensity in both EIA and WB, negative viral load result is conducive to exclude negative subjects from suspects in HIV antibody detections.</p>