AduoLa Fuzhenglin down-regulates microwave-induced expression of β1-adrenergic receptor and muscarinic type 2 acetylcholine receptor in myocardial cells of rats / 生物医学与环境科学(英文)
Biomed. environ. sci
; Biomed. environ. sci;(12): 204-207, 2014.
Article
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| WPRIM
| ID: wpr-270614
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WPRO
ABSTRACT
This paper is aimed to study the effect of ADL on expression of β1-AR and M2-AchR in myocardial cells of rats exposed to microwave radiation. Immunohistochemistry, Western blot and image analysis were used to detect the expression of β1-AR and M2-AchR in myocardial cells at 7 and 14 d after microwave exposure. The results show that the expression level was higher in microwave exposure group and 0.75 g/(kg•d) ADL group than in sham operation group and significantly lower in 1.5 and 3.0 g/(kg•d) ADL groups than in microwave group. So we have a conclusion that the expression of β1-AR and M2-AchR is down-regulated in myocardial cells of rats exposed to microwave radiation. ADL can protect rats against microwave-induced heart tissue injury.
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Asunto principal:
Farmacología
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Medicamentos Herbarios Chinos
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Regulación hacia Abajo
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Ratas Wistar
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Receptores Adrenérgicos beta 1
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Sustancias Protectoras
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Biología Celular
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Receptor Muscarínico M2
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Corazón
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Metabolismo
Límite:
Animals
Idioma:
En
Revista:
Biomed. environ. sci
Año:
2014
Tipo del documento:
Article