Malignant fibrous histiocytoma of the retroperitoneum: an analysis of 31 cases / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 373-374, 2004.
Artículo
en Chino
| WPRIM
| ID: wpr-271010
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the diagnosis and treatment of malignant fibrous histiocytoma of the retroperitoneum (MFHR).</p><p><b>METHODS</b>The clinicopathological features, treatment and prognosis of 31 patients with MFHR were retrospectively analyzed.</p><p><b>RESULTS</b>The mean age of the patients was 52.7 +/- 14.1 years. MaleFemale = 229. The primary symptoms were abdominal mass and pain. The average diameter of tumor was 15 cm. The histopathologic types of the tumor were inflammatory, storiform-pleomorphic, myxoid and giant cell in 16, 10, 4 and 1 cases. The overall survival rate of 1-, 3- and 5-year was 61.3% +/- 9.8%, 31.6% +/- 11.3% and 21.1% +/- 11.4% with a median survival time of 17.0 +/- 6.3 months. Complete resection of the tumor was the major prognostic factor. Postoperative radiotherapy of 20 - 45 Gy was able to prolong the median survival from 12.1 +/- 11.6 months of surgery alone to 26.4 +/- 22.0 months of surgery plus postoperative radiotherapy though without statistical significance (P = 0.051). Postoperative CHOP chemotherapy was not shown to be beneficial.</p><p><b>CONCLUSION</b>Chemotherapy remains the important method of cure. The survival in patients with MFHR might be improved by complete resection combined with chemotherapy or/and radiotherapy.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pancreatectomía
/
Patología
/
Periodo Posoperatorio
/
Pronóstico
/
Neoplasias Retroperitoneales
/
Esplenectomía
/
Cirugía General
/
Terapéutica
/
Vincristina
/
Prednisona
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Oncology
Año:
2004
Tipo del documento:
Artículo
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