Experimental research of hair follicle reconstruction with the aid of embryonic mice dermal cells / 中华整形外科杂志
Chinese Journal of Plastic Surgery
;
(6): 192-196, 2013.
Artículo
en Chino
| WPRIM
| ID: wpr-271232
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect of embryonic dermal signal on the hair-inductive capacity of neonatal mice dermal cells which have been amplified in vitro.</p><p><b>METHODS</b>Embryonic mice dermal cells of embryonic day 14 were added to a chamber on the back of nude mice with neonatal mice dermal cells which had been amplified in vitro for 3 days and freshly isolated neonatal mice epidermal cells. The hair regeneration was compared between the groups with or without embryonic mice dermal cells. Meanwhile, chambers with following cells respectively were constructed as controls embryonic mice dermal cells + neonatal mice epidermal cells; freshly isolated neonatal mice dermal cells + neonatal mice epidermal cells; amplified neonatal mice dermal cells only; embryonic mice dermal cells only; freshly isolated neonatal mice dermal cells only; neonatal mice epidermal cells only.</p><p><b>RESULTS</b>The number of regenerated hairs with the aid of embryonic mice dermal cells (207 +/- 15. 948) was significantly higher than that (67 +/- 8.963) in the group without embryonic mice dermal cells (n = 3, t = 7.653, P = 0.002).</p><p><b>CONCLUSION</b>Embryonic dermal signal can enhance the hair-inductive capacity of neonatal mice dermal cells which have been amplified in vitro.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fisiología
/
Regeneración
/
Piel
/
Cirugía General
/
Células Cultivadas
/
Embriología
/
Trasplante de Células
/
Folículo Piloso
/
Procedimientos de Cirugía Plástica
/
Biología Celular
Límite:
Animales
Idioma:
Chino
Revista:
Chinese Journal of Plastic Surgery
Año:
2013
Tipo del documento:
Artículo
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