Polymorphism of five X-STR loci in Chinese Achang ethnic group / 浙江大学学报·医学版

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the genetic polymorphism and applied value in forensic medicine of five short tandem repeats (STRs) loci(DXS7130, DXS7132, DXS7133, DXS6804 and DXS8378) on X-chromosome in Achang ethnic group.</p><p><b>METHODS</b>Allele frequency and genotype distribution of five X-STR loci among 100 unrelated individuals from Achang ethnic group were analyzed by PCR following polyacrylamide gel electrophoresis and silver staining. Hardy-Weinberg equilibrium of females was tested and forensic parameters were calculated.</p><p><b>RESULT</b>All the five STR loci were polymorphic in Achang ethnic group. Chi-square test indicated that genotype distribution of females was in accordance with Hardy-Weinberg equilibrium.</p><p><b>CONCLUSION</b>These results enrich Chinese genetic database and can be applied to individual identification, paternity testing and population genetics.</p>