Effects of basic fibroblast growth factor on bone marrow mesenchymal stem cell differentiation into temporomandibular joint disc cells / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 732-736, 2012.
Artículo
en Chino
| WPRIM
| ID: wpr-271699
ABSTRACT
The present paper is aimed to observe the effects of basic fibroblast growth factor (bFGF) on bone marrow mesenchymal stem cell (BMSCs) differentiation. The bFGF was used to stimulate BMSCs and histology, immunohistochemistry and enzyme linked immunosorbent assay (ELISA) were used to examine the extracellular matrix produced by induced BMSCs, evaluated the feasibility of BMSCs being the seeding cells of temporomandibular joint (TMJ) disc tissue engineering. The results showed that having been induced with bFGF, the BMSCs could differentiate into fibroblast-like cells, which could synthesize GAG and collagen type I matrix. So it is feasible for BMSCs as seeding cells for engineered TMJ disc.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Farmacología
/
Células de la Médula Ósea
/
Cabras
/
Diferenciación Celular
/
Células Cultivadas
/
Factor 2 de Crecimiento de Fibroblastos
/
Disco de la Articulación Temporomandibular
/
Biología Celular
/
Colágeno Tipo I
/
Ingeniería de Tejidos
Límite:
Animales
Idioma:
Chino
Revista:
Journal of Biomedical Engineering
Año:
2012
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS