Application of beta-cyclodextrin inclusion technique in new dosage form of angelica sinensis essential oil / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 832-845, 2002.
Artículo
en Chino
| WPRIM
| ID: wpr-271798
ABSTRACT
<p><b>OBJECTIVE</b>To make a solid form of Angelica Sinensis essential oil by preparing its inclusion compound with beta-cyclodextrin and evaluate the inclusion rate, dissolution rate and liberating rate of this complex.</p><p><b>METHOD</b>GC-MS, X-ray diffraction and thin-layer chromatography were applied to characterize the essential oil and the inclusion compound.</p><p><b>RESULT</b>The inclusion compound was shown to form a new phase by X-ray diffraction analysis. GC-MS and TLC check-up corroborated the composition of the free oil and the inclusion oil remaining the same.</p><p><b>CONCLUSION</b>The results showed Angelica Sinensis essential oil was more stable with beta-cyclodextrin inclusion. The preparation of this inclusion compound has advantages in limited amount, long time effect, easily preserved and convenient administration as a new dosage form.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Plantas Medicinales
/
Solubilidad
/
Difracción de Rayos X
/
Aceites Volátiles
/
Portadores de Fármacos
/
Química
/
Tecnología Farmacéutica
/
Raíces de Plantas
/
Ciclodextrinas
/
Angelica sinensis
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2002
Tipo del documento:
Artículo
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