Progress of Clinical Trials on Bone Marrow Mesenchymal Stem Cells for Prevention and Therapy of Graft-Versus-Host Disease / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1808-1812, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-272517
ABSTRACT
Graft-versus-host disease (GVHD) is a major complication following allogenetic hematopoietic stem cell transplantation, which shows a great threat to patients' survival and life quality. Along with multiple differentiation potential to various types of progenitor cells, bone marrow mesenchymal stem cells (BMMSC) have been confirmed to possess low immunogenicity and exert favorable immunomodulation. The recent studies show that the safety and high efficiency of BMMSC to prevent and cure GVHD greatly improved survival rate of the hosts. The most recent progress on prevention and therapy of GVHD is summarized in this review based on biology of BMMSC and pathogenesis of GVHD, so as to provide the effective evidence for further research.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Células de la Médula Ósea
/
Células Madre Hematopoyéticas
/
Trasplante de Médula Ósea
/
Trasplante de Células Madre Hematopoyéticas
/
Trasplante de Células Madre Mesenquimatosas
/
Enfermedad Injerto contra Huésped
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Experimental Hematology
Año:
2015
Tipo del documento:
Artículo
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