Periprocedural Hemoglobin Drop and Contrast-Induced Nephropathy in Percutaneous Coronary Intervention Patients
Korean Circulation Journal
;
: 68-73, 2010.
Artículo
en Inglés
| WPRIM
| ID: wpr-27397
ABSTRACT
BACKGROUND AND OBJECTIVES:
The development of contrast-induced nephropathy (CIN) is associated with an increased risk of death and late cardiovascular events after percutaneous coronary intervention (PCI). The relationship between CIN and hemoglobin drop has been controversial. The aim of this study was to evaluate the clinical usefulness of periprocedural hemoglobin drop as a nontraditional risk factor for CIN. SUBJECTS ANDMETHODS:
Five-hundred thirty-seven patients who underwent PCI were divided into 2 groups Group I (486 patients patients who did not develop CIN) and Group II (51 patients patients who developed CIN). All patients were administered iodixanol as contrast media during coronary angiography. CIN is defined as a rise in serum creatinine of > or =25% or > or =0.5 mg/dL above the baseline value within 48 hours after contrast administration.RESULTS:
Baseline clinical and cardiovascular risk factors were not significantly different between the two groups, except for low abdominal circumference (Group I Group II=87.9+/-9.0 cm 81.2+/-15.1 cm, p=0.024), body weight (Group I Group II=63.5+/-10.6 kg 59.7+/-9.2 kg, p=0.008), body mass index (BMI) (Group I Group II=24.4+/-3.4 kg/m2 23.4+/-2.8 kg/m2, p=0.032), pre-PCI hemoglobin (Group I Group II=13.2+/-2.0 g/dL 12.3+/-2.0 g/dL, p=0.003), and post-PCI hemoglobin (Group I Group II=12.4+/-1.9 g/dL 11.5+/-1.8 g/dL, p=0.001). Multiple logistic regression analysis showed that a periprocedural drop in hemoglobin (>1 g/dL) was an independent predictor of CIN, like other known risk factors.CONCLUSION:
A periprocedural drop in hemoglobin of more than 1 g/dL is another important independent predictor for CIN, even in patients administered the lowest nephrotoxic contrast agent, iodixanol, during PCI.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Ácidos Triyodobenzoicos
/
Peso Corporal
/
Hemoglobinas
/
Índice de Masa Corporal
/
Modelos Logísticos
/
Factores de Riesgo
/
Angiografía Coronaria
/
Medios de Contraste
/
Creatinina
/
Insuficiencia Renal
Tipo de estudio:
Estudio de etiología
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Humanos
Idioma:
Inglés
Revista:
Korean Circulation Journal
Año:
2010
Tipo del documento:
Artículo
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