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Research Progress on Cytometric Bead Assay for Platelet Antibody Detection / 中国实验血液学杂志
Journal of Experimental Hematology ; (6): 1208-1211, 2015.
Artículo en Chino | WPRIM | ID: wpr-274064
ABSTRACT
Anti-platelet specific antibody is one of the most important reasons leading to thrombocytopenia and megakaryocyte dysmaturity. The detection of platelet autoantibodies is an important step in the diagnosis of ITP because of the absence of specific clinic feature. The monoclonal antibody-specific immobilization of platelet antigens (MAIPA) has become a "gold standard" for determination of PLT specific antibody, which has high specificity and low sensitivity. However, this assay is time-consuming and tedious work. Routine use of this assay in hospital is difficult. Recently, some researches reporded the cytometric bead assay that has higher sensitivity than MAIPA, and so probably solves the problem of time-consuming partly, that also can use different beads for simultaneous detection. This review focuses on recent progress of the cytometric bead assay.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Trombocitopenia / Plaquetas / Megacariocitos / Antígenos de Plaqueta Humana / Anticuerpos / Anticuerpos Monoclonales Tipo de estudio: Estudio diagnóstico Límite: Humanos Idioma: Chino Revista: Journal of Experimental Hematology Año: 2015 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Trombocitopenia / Plaquetas / Megacariocitos / Antígenos de Plaqueta Humana / Anticuerpos / Anticuerpos Monoclonales Tipo de estudio: Estudio diagnóstico Límite: Humanos Idioma: Chino Revista: Journal of Experimental Hematology Año: 2015 Tipo del documento: Artículo