Advances in researches on genetic predisposition to steroid-induced osteonecrosis of the femoral head / 中国骨伤
China Journal of Orthopaedics and Traumatology
;
(12): 156-159, 2010.
Artículo
en Chino
| WPRIM
| ID: wpr-274457
ABSTRACT
The pathogenesis of steroid-induced osteonecrosis of the femoral head (SONFH) is not very clear at present. For the past few years researches showed that the SONFH related to genetic predisposing factors. The related research progresses were reviewed in this article to show the correlation between genetic mutation and genetic polymorphism of steroid metabolism and transport, resistance and receptor, coagulation and fibrinolysis, lipid and bone metabolism and susceptibility to SONFH. The article also discussed current problems, countermeasure and future applications.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Receptores de Glucocorticoides
/
Miembro 1 de la Subfamilia B de Casetes de Unión a ATP
/
Subfamilia B de Transportador de Casetes de Unión a ATP
/
Predisposición Genética a la Enfermedad
/
Polimorfismo de Nucleótido Simple
/
Citocromo P-450 CYP3A
/
Metabolismo de los Lípidos
/
Necrosis de la Cabeza Femoral
/
Genética
/
Glucocorticoides
Límite:
Humanos
Idioma:
Chino
Revista:
China Journal of Orthopaedics and Traumatology
Año:
2010
Tipo del documento:
Artículo
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