Studies on the chemical constituents of Lycianthes biflora / 药学学报

ABSTRACT

<p><b>AIM</b>To study the chemical constituents of Lycianthes biflora.</p><p><b>METHODS</b>Column chromatography was used to separate the chemical constituents. IR, MS, 1HNMR, 13CNMR and 2D-NMR technique were used to determine the structures of the isolated constituents.</p><p><b>RESULTS</b>Five compounds were isolated from this plant. Their structures were identified to be bifloride A (1), N-trans-cinnamoyltyramine (2), liquiritigenin (3), N-trans-p-coumaroyloctopamine (4), 1-O-beta-D-glucopyranosyl-2-N-2'-hydroxypalmitoyl-sphinga-4- trans-8-trans-dienine (5).</p><p><b>CONCLUSION</b>Compounds 1 and 2 are new compounds, the others were isolated from this plant for the first time. Compound 2 showed inhibitory effects on P-388.</p>