Clinicopathologic characteristics and postoperative prognosis in colorectal cancer with peritoneal dissemination / 中华外科杂志
Chinese Journal of Surgery
;
(12): 1634-1637, 2008.
Artículo
en Chino
| WPRIM
| ID: wpr-275963
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the correlation between clinicopathologic factors and peritoneal dissemination in colorectal cancer, and the impact of surgery on the prognosis of patients with peritoneal dissemination.</p><p><b>METHODS</b>Based on the clinical database built in 1994, the clinicopathologic data and the result of follow-up of all colorectal cancer patients were analyzed retrospectively.</p><p><b>RESULT</b>One hundred and fifty cases (7.40%) in all 2019 patients with primary colorectal cancer were found complicated with peritoneal dissemination. The clinicopathologic factors in patients with peritoneal dissemination were significantly correlated with tumor penetrating through serosa, lymph node metastasis, undifferentiated carcinoma, ascites, different pathological type, circumference of tumor, neoplastic intestinal obstruction, and Dukes staging. Peritoneal dissemination was associated with tumor penetrating through serosa, different pathological type on multivariate analysis. The 1-, 3-, 5-year survival rate of the patients with peritoneal dissemination were 70.4%, 38.1%, 30.2%; The 1-, 3-, 5-year survival rate of the patients undergoing radical resection were significant better than those in the cases undergoing palliative operation or palliative resection (P < 0.05).</p><p><b>CONCLUSIONS</b>Colorectal cancer complicated with peritoneal dissemination has poorer clinicopathologic characteristics. Those with local peritoneal dissemination has rather better prognosis than those with wide peritoneal dissemination. Radical resection of the disseminated tumor can improve the prognosis of the patients.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Neoplasias Peritoneales
/
Pronóstico
/
Cirugía General
/
Neoplasias Colorrectales
/
Análisis de Supervivencia
/
Estudios Retrospectivos
/
Estudios de Seguimiento
/
Invasividad Neoplásica
/
Siembra Neoplásica
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Surgery
Año:
2008
Tipo del documento:
Artículo
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