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Induced pluripotent stem cells in spermatogenesis: Progress in current studies / 中华男科学杂志
National Journal of Andrology ; (12): 925-930, 2015.
Artículo en Chino | WPRIM | ID: wpr-275993
ABSTRACT
Spermatogenesis is a complex process. Current knowledge about human spermatogenesis is mainly based on the mouse model while little is known about the initial stage of this fundamental process in humans. The establishment of the model of spermatogenesis in vitro may contribute to an overall understanding of male germ cell development, an insight into the mechanisms of infertility, and clinical management of male infertility. This review summarizes current knowledge about the generation of germ cell-like cells from induced pluripotent stem cells (iPSCs) in vitro and discusses the potential application of iPSCs in the treatment of male infertility.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Espermatogénesis / Terapéutica / Diferenciación Celular / Células Madre Pluripotentes Inducidas / Células Germinativas / Infertilidad Masculina Límite: Animales / Humanos / Masculino Idioma: Chino Revista: National Journal of Andrology Año: 2015 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Espermatogénesis / Terapéutica / Diferenciación Celular / Células Madre Pluripotentes Inducidas / Células Germinativas / Infertilidad Masculina Límite: Animales / Humanos / Masculino Idioma: Chino Revista: National Journal of Andrology Año: 2015 Tipo del documento: Artículo