Intracytoplasmic sperm injection does not improve the clinical outcomes of the males with 100% teratozoospermia / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate whether intracytoplasmic sperm injection (ICSI) can improve the clinical outcomes of the male patients with 100% teratozoospermia.</p><p><b>METHODS</b>We retrospectively analyzed the clinical data of 152 couples undergoing in vitro fertilization-embryo transfer (IVF-ET), including 75 cycles of IVF and 77 cycles of ICSI. We compared the rates of normal fertilization, high-quality embryos, transferrable embryos, implantation, clinical pregnancy, and abortion between the two groups.</p><p><b>RESULTS</b>In the 100% teratozoospermia patients the number of transferrable embryos was significantly lower in the IVF than in the ICSI group (78.91% vs 84.92%, P < 0.05), while the rates of normal fertilization and implantation were higher in the former than in the latter (60.26% vs 57.87% and 48.00% vs 39.55%, both P > 0.05). There were no statistically significant differences between the two groups in the female age, Gn days, Gn dose, BMI, infertility duration, endometrial thickness, and basal serum FSH and E2.</p><p><b>CONCLUSION</b>ICSI cannot improve the clinical outcomes of the male patients with 100% teratozoospermia.</p>