Effects of processing Phellodendron amurense with salt on anti-gout / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the effects of processing Phellodendron anurene with salt on anti-gout.</p><p><b>METHOD</b>The mouse serum uric acid level and liver xanthine oxidase activity were used to evaluate anti-gout effects of raw and processing P. amurense with salt.</p><p><b>RESULT</b>Both raw and processing P. amurense with salt reduced serum uric acid levels in the in hyperuricemic mice, and inhibited activities of liver xanthine oxidase at the low and high doses respectively, thus exhibiting anti-gout effects. Moreover, they showed the tendency to decrease the uric acid levels in the normal animal only at the high dose. The latter was a little weaker than the former.</p><p><b>CONCLUSION</b>Processing with salt might not significantly change anti-gout effect of P. amurense.</p>