Electroclinical features of myoclonic-atonic epilepsy / 中华儿科杂志
Chinese Journal of Pediatrics
;
(12): 577-582, 2011.
Artículo
en Chino
| WPRIM
| ID: wpr-276996
ABSTRACT
<p><b>OBJECTIVE</b>To summarize the electroclinical characteristics of myoclonic atonic epilepsy (MAE) in children.</p><p><b>METHOD</b>The clinical data, video electroencephalogram (EEG) and simultaneous electromyography (EMG) of MAE patients were analyzed. The treatment and its effects were followed up.</p><p><b>RESULT</b>In 47 MAE patients, 25 had a history of febrile seizures (FS), 20 had a family history of FS or epilepsy. All patients had a normal development before the illness. The age of afebrile seizure onset was between 1.4 years to 5.8 years. The first seizure was generalized tonic-clonic seizure (GTCS) in 41 patients (87.2%). All patients had multiple seizure types, including 47 GTCS (97.9%), 34 myoclonic atonic seizures (72.3%), 47 myoclonic seizures (100%), 32 atonic seizures (68.1%), 36 atypical absences (76.6%) and 3 tonic seizures (6.4%). EEG backgrounds were slow or parietal θ rhythm, interictal EEG showed 1-4 Hz (predominant 2-3 Hz) generalized spike and wave or poly spike and wave discharges in all cases. Seizures were controlled by antiepileptic drugs (AEDs) in 41 patients (87.2%). Valproate was used in 37. Lamotrigine was used in 26. Mild mental retardation was observed in 10 children after the onset of the illness.</p><p><b>CONCLUSION</b>The clinical features of MAE included the following the development was normal before the onset of the illness; the onset of seizure type was often GTCS. All patients had multiple generalized seizure types. Myoclonic atonic seizure was its characteristic seizure type. EEG showed generalized discharges. Early diagnosis and rational choice of AEDs are important for getting a better prognosis.</p>
Texto completo:
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Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Terapéutica
/
Epilepsia Generalizada
/
Epilepsias Mioclónicas
/
Diagnóstico
/
Electroencefalografía
Tipo de estudio:
Estudio diagnóstico
/
Estudio pronóstico
/
Estudio de tamizaje
Límite:
Niño
/
Child, preschool
/
Femenino
/
Humanos
/
Lactante
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Pediatrics
Año:
2011
Tipo del documento:
Artículo
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