Application of multiparameter flow cytometry in diagnosis of non-Hodgkin lymphoma / 中华病理学杂志
Chinese Journal of Pathology
;
(12): 203-208, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-277442
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the role and application of flow cytometry in the diagnosis of non-Hodgkin lymphoma (NHL).</p><p><b>METHODS</b>Fresh cell samples from 40 cases of lymphoproliferative disorders were obtained by fine needle aspiration or excisional biopsies. Multiparameter flow cytometry was used to study the surface antigens of lymphoid cells. The immunophenotyping results were also correlated with morphologic features seen in the cytology preparations.</p><p><b>RESULTS</b>Of the 40 cases with histologic diagnosis of NHL, 37 cases (92.5%) had the lymphoma diagnosis confirmed by this method. The concordance rate for the 20 cases of B-cell NHL was 100%. As for the 17 cases with histologic diagnosis of T-cell NHL, 12 cases (66.7%) were correctly diagnosed as T-cell NHL using flow cytometry, while 2 cases (11.8%) were interpreted as B-cell NHL and the remaining 3 cases (17.6%) were undiagnosed.</p><p><b>CONCLUSION</b>Immunophenotyping by flow cytometry can serve as an ancillary technique in diagnosis and subclassification of NHL.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Linfoma no Hodgkin
/
Reproducibilidad de los Resultados
/
Inmunofenotipificación
/
Linfoma de Células B
/
Linfoma de Células T
/
Sensibilidad y Especificidad
/
Biopsia con Aguja Fina
/
Diagnóstico
/
Alergia e Inmunología
Tipo de estudio:
Estudio diagnóstico
Límite:
Adolescente
/
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Pathology
Año:
2006
Tipo del documento:
Artículo
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