Prevalence of microalbuminuria and its related factors among different genders in general population of Beijing / 中华流行病学杂志

ABSTRACT

Objective Microalbuminuria (MAU) is generally defined as an early effective index of cardiovascular disease and renal disease. Our study aims to investigate the prevalence of MAU and its related factors among people living in Bcijing. Methods In a cross-sectional study,2080 subjects (810 men and 1270 women) are recruited, with age distribution as 50.87± 13.10 years (mean ± standard deviation). Urine albumin-creatinine ratio (ACR) is used to screen for microalbuminuria. All the data is analyzed with multivariate logistic regression method to explore the related factors for MAU. Results The overall prevalence of MAU in general population of Beijing is 17.50%, with male as 15.43% and female as 18.82% (P＜0.05). Results from the multivariate logistic regression analysis reveal that the independent risk factors of MAU in men are age(OR= 1.02), blood pressure ( OR= 1.02 ), serum creatinine ( OR= 1.04), while age ( OR= 1.04), systolic blood pressure (OR = 1.02), serum creatinine ( OR = 1.08 ), body mass index ( OR= 1.07), total cholesterol ( OR=2.05) in women. The protective factor of MAU in women is H DL-C (OR=0.44). Conclusion Our findings indicate that the prevalence of MAU in Beijing area is higher than those in other areas in China or abroad. The prevalence in females is higher than that in males (P＜0.05). There is a gender difference in the related factors of MAU.