Annotation of complete genomic sequence of 3p24-p25 478 kb of human DNA / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 259-263, 2002.
Artículo
en Chino
| WPRIM
| ID: wpr-278187
ABSTRACT
<p><b>OBJECTIVE</b>To annotate the human genome 3p24-p25 478 kb complete sequence.</p><p><b>METHODS</b>The protein-coding genes in the genomic sequence were identified by using ab initio gene finding, homology-based similarity database searching and all or partial mRNA aligning with genomic sequence, and the content feature of the genomic sequence were analyzed by using EMBOSS package.</p><p><b>RESULTS</b>Two known genes SLC6A1 and SLC6A11 were identified; as well as the GC content of this genomic sequence was 47% and 3 putative CpG islands were predicted in the genomic sequence, located in 130,685-131,516 bp, 307,090-307,870 bp and 415,585-416,308 bp, respectively.</p><p><b>CONCLUSIONS</b>The methods, as mentioned above, might be used for annotating the biological information in the genomic sequence, such as gene structure, GC content, CpG island.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Cromosomas Humanos Par 3
/
Datos de Secuencia Molecular
/
Secuencia de Bases
/
Genoma Humano
/
Proyecto Genoma Humano
/
Mapeo Cromosómico
/
Cromosomas Artificiales Bacterianos
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
Idioma:
Chino
Revista:
Acta Academiae Medicinae Sinicae
Año:
2002
Tipo del documento:
Artículo
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