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Antifungal active triterpene glycosides from sea cucumber Holothuria scabra / 药学学报
Acta Pharmaceutica Sinica ; (12): 620-624, 2009.
Artículo en Inglés | WPRIM | ID: wpr-278209
ABSTRACT
To study the new antifungal active triterpene glycosides of sea cucumber Holothuria scabra. Triterpene glycosides from Holothuria scabra were separated and purified by silica gel chromatography, reversed-phase silica gel chromatography and RP-HPLC. Their structures were elucidated on the basis of spectral data and chemical evidence. Three triterpene glycosides were identified as scabraside A (1), echinoidea A (2) and holothurin A1 (3). Scabraside A (1) is a new triterpene glycoside, and compounds 2 and 3 were isolated from Holothuria scabra for the first time. They showed antifungal activities (1 < or = MIC80 < or = 16 microg mL(-1)).
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Farmacología / Triterpenos / Estructura Molecular / Química / Holothuria / Glicósidos / Holoturina / Antifúngicos Límite: Animales Idioma: Inglés Revista: Acta Pharmaceutica Sinica Año: 2009 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Farmacología / Triterpenos / Estructura Molecular / Química / Holothuria / Glicósidos / Holoturina / Antifúngicos Límite: Animales Idioma: Inglés Revista: Acta Pharmaceutica Sinica Año: 2009 Tipo del documento: Artículo