Recent advance in the study of novel anti-tumor targets and drugs--aurora kinase and Pin1 / 药学学报
Acta Pharmaceutica Sinica
;
(12): 264-269, 2009.
Artículo
en Chino
| WPRIM
| ID: wpr-278272
ABSTRACT
Malignant tumor, one of the most refractory diseases, plays a threaten role in human health, the therapy and research on malignant tumor have taken a long way to go. The anti-tumor drugs which are the essential therapy strategies upgrade with the development of new anti-tumor targets and the research on tumor pathogenesis. Aurora kinase and Pin1, the novel anti-tumor targets, maintain the important relationship with tumor. Many new compounds designed on these targets have excellent anti-tumor effects and also enter into phase I or phase II clinical trial.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Farmacología
/
Piperazinas
/
Naftoquinonas
/
Proteínas Serina-Treonina Quinasas
/
Apoptosis
/
Isomerasa de Peptidilprolil
/
Aurora Quinasas
/
Peptidilprolil Isomerasa de Interacción con NIMA
/
Metabolismo
Límite:
Humanos
Idioma:
Chino
Revista:
Acta Pharmaceutica Sinica
Año:
2009
Tipo del documento:
Artículo
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