Effect of angiotensin II on potassium channels of ischemic ventricular myocytes of the guinea pig / 生理学报
Acta Physiologica Sinica
;
(6): 149-153, 2002.
Artículo
en Chino
| WPRIM
| ID: wpr-279321
ABSTRACT
The experiments were carried out on guinea pig isolated ventricular myocytes by using whole-cell patch clamp. The effects of angiotensin II (Ang II) on potassium ion channels of acute ischemic myocytes were observed. Whole-cell patch clamp recordings showed that physiological potassium current, including delayed rectifier potassium current and inward rectifier potassium current were inhibited under the condition of simulated ischemia, and then further inhibited by treatment with Ang II. ATP-sensitive potassium currents were increased under simulated ischemia and were further enhanced by Ang II treatment.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Farmacología
/
Fisiología
/
Angiotensina II
/
Canales de Potasio
/
Células Cultivadas
/
Isquemia Miocárdica
/
Biología Celular
/
Miocitos Cardíacos
/
Cobayas
Límite:
Animales
Idioma:
Chino
Revista:
Acta Physiologica Sinica
Año:
2002
Tipo del documento:
Artículo
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