Distribution of neuropeptide Y-like immunoreactive fiber in rat temporomandibular joint / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 323-329, 2002.
Artículo
en Chino
| WPRIM
| ID: wpr-279621
ABSTRACT
<p><b>OBJECTIVE</b>This investigation aimed at explore the total distribution of neuropeptide Y-like immunoreactive (NPY-LI) fibers and their changes post-trauma in rat temporomandibular joints (TMJs).</p><p><b>METHODS</b>Six groups of rats were killed individually before trauma, 1, 3, 7, 14 and 28 days after trauma. TMJs were extracted totally, and the avidin-biotin-peroxidase complex method and image analysis were employed to detect NPY-LI fibers in frozen sections of TMJs.</p><p><b>RESULTS</b>NPY-LI fibers were distributed extensively in TMJs, except the central disc band and bone, and they were mainly located around blood vessels, especially arteries. The densities of fibers in the six groups were 160.4 +/- 27.5, 95.8 +/- 16.4, 88.6 +/- 14.5, 114.3 +/- 17.0, 135.0 +/- 20.7, 158.6 +/- 19.5 (unitmm2).</p><p><b>CONCLUSION</b>NPY-LI nerve fibers are distributed extensively in the periphery of blood vessels of TMJs and densities changed dynamically when TMJs were impacted. NPY may play an important role in pathologic change of TMJ by regulating local blood circulation.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Fisiología
/
Articulación Temporomandibular
/
Neuropéptido Y
/
Procesamiento de Señales Asistido por Computador
/
Ratas Sprague-Dawley
/
Metabolismo
/
Fibras Nerviosas
Límite:
Animales
Idioma:
Chino
Revista:
West China Journal of Stomatology
Año:
2002
Tipo del documento:
Artículo
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