Genotype of Rotavirus Vaccine Strain LLR in China is G10P15 / 病毒学报
Chinese Journal of Virology
;
(6): 170-173, 2015.
Artículo
en Chino
| WPRIM
| ID: wpr-280278
ABSTRACT
Rotavirus is the leading causal agent of severe acute gastroenteritis in children aged <5 years. A specific pharmacologic agent for the treatment of rotavirus-infected children is lacking. In China, only the Luo Tewei oral vaccine (Lanzhou Institute of Biological Products, Shanghai, China), which is produced from Lanzhou lamb rotavirus vaccine (LLR), is available. Studies have hypothesized that the genotype of LLR is G10P[12], To identify the genotype of LLR by reverse transcription-polymerase chain reaction, we showed that the VP7 and VP4 genotypes of LLR were G10 and P[15], respectively, based on sequencing, alignment and phylogenetic analyses. In conclusion, we identified the genotype of rotavirus strain LLR to be G10P[15].
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Filogenia
/
Infecciones por Rotavirus
/
Proteínas Virales
/
Virología
/
Datos de Secuencia Molecular
/
Química
/
China
/
Clasificación
/
Homología de Secuencia de Aminoácido
/
Rotavirus
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
Chinese Journal of Virology
Año:
2015
Tipo del documento:
Artículo
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