Mechanism of CD4+CD25+ and CD8+ regulatory T cells--review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1137-1140, 2005.
Artículo
en Chino
| WPRIM
| ID: wpr-280750
ABSTRACT
Regulatory T cells (Treg) play a key role in the negative regulation of the immune system, which can inhibit inappropriate self-reactive T cells, as well as limit the range, extent and lasting time of immune responses, so as to inhibit the proliferation of CD4(+) and CD8(+) effector T cells. In view of these properties, there is little doubt about the enormous potential value of Tregs in molecular mechanisms and clinical treatment of human autoimmune disorders, graft-versus-host disease (GVHD) and allergies. In this review, the molecular mechanisms of CD4(+)CD25(+) Treg and CD8(+) Treg were mainly discussed, and challenge with which study on Treg cells is faced and prospects were briefly described.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Enfermedades Autoinmunes
/
Linfocitos T Reguladores
/
Linfocitos T CD8-positivos
/
Alergia e Inmunología
/
Subunidad alfa del Receptor de Interleucina-2
/
Enfermedad Injerto contra Huésped
Límite:
Humanos
Idioma:
Chino
Revista:
Journal of Experimental Hematology
Año:
2005
Tipo del documento:
Artículo
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