Nephron-sparing surgery for 69 patients with renal tumors / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the results of nephron-sparing surgery (NSS) for renal tumors.</p><p><b>METHODS</b>A retrospective analysis was performed for the clinical data of 66 patients who were affected by renal tumors and treated with NSS.</p><p><b>RESULTS</b>Among 66 cases, 63 were treated with partial nephrectomy and 6 with enucleation. The renal vessel was clamped in 45 cases intraoperative. The histological subtypes included clear cell carcinoma in 40 cases, papillary renal cell carcinoma (RCC) in 2 cases, chromophobe RCC in 2 cases, angiomyolipoma in 24 cases, and adenoma in one case. Surgical margins were negative in all cases. Seven patients had postoperative complications and no perioperative acute renal failure occurred. Among 44 cases with renal cell carcinoma, 42 were followed for mean 55.4 months. The overall and disease-free 5-year survival rates were 97.3% and 90.7%, respectively.</p><p><b>CONCLUSION</b>NSS is a effective and safe operation for selected patients with renal tumors, providing functional advantage gained by the maximal preservation of unaffected renal parenchyma without sacrificing cancer control.</p>