Studies on liver-toxicity in rhigoma of Dioscorea bulbifera / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 661-663, 2003.
Artículo
en Chino
| WPRIM
| ID: wpr-282200
ABSTRACT
<p><b>OBJECTIVE</b>To explore the liver-toxic fraction in Rhigoma of Dioscorea bulbifera.</p><p><b>METHOD</b>The rats were randomized into four groups control group (20% PVP-water), T001(10% total methanol extraction), F002(5% chloroform fraction) and F003(5% methanol fraction). Direct bilirubin (DBil) and Glutamic-pyruvic transaminase (GPT) were examined, and liver index was measured. The histological and morphological observations were performed with optical and electrical microscope.</p><p><b>RESULT</b>T001 and F002 showed significant liver toxicity.</p><p><b>CONCLUSION</b>The chloroform fraction was the liver-toxic fraction of D. bulbifera.</p>
Texto completo:
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Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Plantas Medicinales
/
Bilirrubina
/
Sangre
/
Medicamentos Herbarios Chinos
/
Distribución Aleatoria
/
Química
/
Ratas Sprague-Dawley
/
Dioscorea
/
Alanina Transaminasa
Límite:
Animales
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2003
Tipo del documento:
Artículo
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