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The impact of N, N-dimethylacetamide on the health of workers / 中华劳动卫生职业病杂志
Chinese Journal of Industrial Hygiene and Occupational Diseases ; (12): 834-836, 2011.
Artículo en Chino | WPRIM | ID: wpr-282489
ABSTRACT
<p><b>OBJECTIVE</b>To explore the hepatic toxicity and the exposure biomarkers of N, N-Dimethylacetamide.</p><p><b>METHODS</b>One hundred forty five objects were chosen by stratified random sampling method. The investigation was performed using questionnaire and physical examination. The air concentrations of DMAC in the workshops were monitored. The urine samples were collected and analyzed after work everyday or at the weekend. The correlation between the air concentrations of DMAC in the workshops and the concentrations of urinary NMAC wee analyzed by regression.</p><p><b>RESULTS</b>The air concentration of DMAC in the spinning workshop was higher than others. The morbidity of abnormal hepatic function was 12.4%, 61.1% of workers with abnormal hepatic function appeared in one year after exposure to DMAC in the workshops ( r=0.44, P<0.01).</p><p><b>CONCLUSION</b>The abnormal heptic function was found in workers exposed to DMAC for short period. The concentration of urinary NMAC can serve as the exposure biomarker of DMAC.</p>
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Orina / Biomarcadores / Monitoreo del Ambiente / Encuestas y Cuestionarios / Exposición Profesional / Lugar de Trabajo / Contaminantes Ocupacionales del Aire / Toxicidad / Pruebas de Función Hepática / Acetamidas Límite: Adolescente / Adulto / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Industrial Hygiene and Occupational Diseases Año: 2011 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Orina / Biomarcadores / Monitoreo del Ambiente / Encuestas y Cuestionarios / Exposición Profesional / Lugar de Trabajo / Contaminantes Ocupacionales del Aire / Toxicidad / Pruebas de Función Hepática / Acetamidas Límite: Adolescente / Adulto / Humanos / Masculino Idioma: Chino Revista: Chinese Journal of Industrial Hygiene and Occupational Diseases Año: 2011 Tipo del documento: Artículo