Multivariate analysis of the risk factors of cytomegalovirus pneumonia after renal transplantation / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1182-1184, 2009.
Artículo
en Chino
| WPRIM
| ID: wpr-282587
ABSTRACT
<p><b>OBJECTIVE</b>To identify the risk factors for cytomegalovirus (CMV) pneumonia after renal transplantation and investigate the early precaution measures.</p><p><b>METHODS</b>A retrospective study was conducted in a group of 28 patients undergoing renal transplantation who were readmitted because of CMV pneumonia between Jan, 2005 and Dec, 2007. Chi-square test and multivariate logistic regression were used to identity the significant risk factors.</p><p><b>RESULTS</b>Seven factors, namely recipient age, acute graft rejection, pre-transplantation dialysis, delayed graft function recovery, recipient peak PRA level, donor CMV positivity and the use of MMF were found to significantly correlate to post-transplant CMV pneumonia. Multivariate logistic regression further confirmed that donor CMV IgG positivity, acute graft rejection and pre-transplantation dialysis for over 6 months were independent factors to predict the occurrence of CMV pneumonia.</p><p><b>CONCLUSIONS</b>Acute graft rejection control, appropriate donor selection and shortened dialysis before the transplantation can be crucial factors to reduce the incidence of CMV pneumonia after renal transplantation.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Neumonía Viral
/
Complicaciones Posoperatorias
/
Análisis Multivariante
/
Estudios Retrospectivos
/
Factores de Riesgo
/
Factores de Edad
/
Diálisis Renal
/
Trasplante de Riñón
/
Infecciones por Citomegalovirus
/
Rechazo de Injerto
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Journal of Southern Medical University
Año:
2009
Tipo del documento:
Artículo
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