Expression of aquaporin-1 in human oligohydramnios placenta and fetal membranes / 南方医科大学学报
Journal of Southern Medical University
; (12): 1130-1132, 2009.
Article
en Zh
| WPRIM
| ID: wpr-282603
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To detect aquaporin-1 mRNA (AQP1) expression in human oligohydramnios placenta and fetal membranes.</p><p><b>METHODS</b>Placenta and fetal membranes samples were obtained from 5 women with oligohydramnios and 5 with normal amniotic fluid volume. AQP-1 mRNA expression in the tissue samples was detected by semi-quantitative RT-PCR.</p><p><b>RESULTS</b>The expression of AQP1 mRNA was significantly lower in oligohydramnios placenta than in normal pregnancy placenta at term (P<0.05), and also significantly lower in oligohydramnios fetal membranes than in normal fetal membranes at term (P<0.05).</p><p><b>CONCLUSION</b>Alterations in AQP1 mRNA expressions in human placenta and fetal membranes may play an important role in the disorder of maternal-fetal fluid exchange and amniotic fluid volume.</p>
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Placenta
/
Tercer Trimestre del Embarazo
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ARN Mensajero
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Oligohidramnios
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Acuaporina 1
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Membranas Extraembrionarias
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Genética
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Metabolismo
Límite:
Adult
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Female
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Humans
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Pregnancy
Idioma:
Zh
Revista:
Journal of Southern Medical University
Año:
2009
Tipo del documento:
Article