Patterns and prognostic value of resection margin involvement and lateral pelvic metastases for patients with rectal cancer / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 474-476, 2006.
Artículo
en Chino
| WPRIM
| ID: wpr-283294
ABSTRACT
<p><b>OBJECTIVE</b>To study the patterns and prognostic value of resection margin involvement and lateral pelvic metastases, providing surgeons with pathologic proofs of tumor spread within the studied areas.</p><p><b>METHODS</b>Large tissue slices of 62 specimens from patients with rectal cancer were used in the pathologic study and the outcomes were followed.</p><p><b>RESULTS</b>Compared with patients without margin involvement, patients with circumferential margin involvement (CMI), seen in 8 cases (12.9%), had poorer postoperative survival (P=0.003). The 12 patients (19.4%) with lateral pelvic metastases suffered poorer survival, compared with those without lateral pelvic metastases (P=0.026). Eight patients (66.7%) were diagnosed to have single lateral pelvic region involved, while the other 4 had multiple regions involved. The incidence of lateral metastases differed among regions, with higher occurrence in the root of middle rectal artery (6/12, 50.0%), area of the internal iliac artery (4/12, 33.3%) and the obturator region (3/12, 25.0%).</p><p><b>CONCLUSION</b>Occurrence of CMI or lateral metastases in rectal cancer patients predispose poor survival, thus a more radical clearance and postoperative adjuvant therapy are recommended.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Pelvis
/
Neoplasias del Recto
/
Estudios de Seguimiento
/
Mortalidad
/
Supervivencia sin Enfermedad
/
Mesenterio
/
Invasividad Neoplásica
/
Metástasis de la Neoplasia
/
Estadificación de Neoplasias
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Chinese Journal of Gastrointestinal Surgery
Año:
2006
Tipo del documento:
Artículo
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