The study of effects of static magnetic field on SP-mRNA in trigeminal ganglion in rats / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 235-237, 2003.
Artículo
en Chino
| WPRIM
| ID: wpr-283612
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the effect of static magnetic field on the expression of SP-mRNA in TG in rats.</p><p><b>METHODS</b>44 Wistar rats aged 6-7 weeks were put into static magnetic field and were sacrificed at 1 h, 2 h, 6 h, 12 h, 24 h, respectively. In situ hybridization method was used to evaluate the changes of SP-mRNA expression at different time point.</p><p><b>RESULTS</b>Many neurons in TG were marked with SP probes in each group, the expression of SP-mRNA increased remarkably in static magnetic field group. In this group, the percentage of SP-mRNA positive neurons in TG increased greatly in 1 h, reached its peak in 2 h, from then on, decrease of the percentage started slowly but a moderate percentage was kept until 24 h, which was thought to be enough to maintain orthodontic tooth movement. The tendency of control group was almost the same with that of experimental group. The expression of SP-mRNA was higher in experimental group within 2 h but became lower after 2 h as compared with control group, this indicated that magnetic field reduced the SP-mRNA expression and exerted restoring effect on trauma. There were significant differences between experimental groups and control group at different time points (P < 0.01).</p><p><b>CONCLUSION</b>The expression of SP-mRNA in TG in rats increased significantly in static magnetic field.</p>
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Efectos de la Radiación
/
ARN Mensajero
/
Distribución Aleatoria
/
Sustancia P
/
Ganglio del Trigémino
/
Ratas Wistar
/
Campos Electromagnéticos
/
Genética
/
Metabolismo
Límite:
Animales
Idioma:
Chino
Revista:
West China Journal of Stomatology
Año:
2003
Tipo del documento:
Artículo
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