Prepared evening primrose oil microspheres by spray drying / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To explore the best technique parameters on preparing evening primrose oil microspheres by spray drying technique.</p><p><b>METHOD</b>GC and internal standard method were used to determine the content of gamma-linolenic acid methyl esters, the technological parameters were investigated by orthogonal experimental design with the yield and entrapment rate as indexes.</p><p><b>RESULT</b>The charging rate as 3 mL x min(-1), atomizing pressure as 100 kPa and the temperature of inlet as 105 degrees C were the best technique parameters.</p><p><b>CONCLUSION</b>Evening primrose oil microspheres accorded with the expecting demand. The main influencing factor is the charging rate. Spray drying is reasonable and practical for preparing evening primrose oil microspheres.</p>