Separation and purification technology of main active composition of Hongye Xingtong soft capsules with macroporous resin / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the technical conditions of the extraction and purification of the active composition from Polygonum orientale and Crataegus pinnatifida Bge. in Hongye Xingtong soft capsules with the macroporous resin.</p><p><b>METHOD</b>The orientm, isorientm and hyperoside were used as index to screen the five kinds of resins. And the technical conditions of the enrichment and purification of D101 resin selected out of above were all-round studied.</p><p><b>RESULT</b>The D101 was fit for adsorbing orientm, isorientm and hyperoside. Under the optimal conditions, the transfer rate of orientm, isorientm and hyperoside was above 91%, and the total solid was cut down by more than 60%.</p><p><b>CONCLUSION</b>The D101 is greatly effective for the enrichment and purification of the active composition of P. orientale and C. pinnatifida Bge.</p>