Effect of zhitiaokang capsule on serum insulin-like growth factor-2 in patients with hyperlipidemia / 中国中西医结合杂志

ABSTRACT

<p><b>OBJECTIVE</b>To observe the effect of Zhitiaokang capsule (ZTK) on serum insulin-like growth factor-2 (IGF-2) in patients with hyperlipidemia (HLP).</p><p><b>METHODS</b>Patients with HLP were randomly divided into the treated group (n = 124) and the control group (n = 62), they were treated by ZTK and Zhibituo tablet respectively for 8 weeks as one therapeutic course. The changes of blood lipids and serum IGF-2 before and after treatment were observed.</p><p><b>RESULTS</b>ZTK could significantly reduce blood lipids and increase serum content of IGF-2.</p><p><b>CONCLUSION</b>ZTK could improve the insulin resistant status and inhibit the development of hyperlipidemia in patients by means of raising serum content of IGF-2 and suppressing vascular endothelial cell apoptosis.</p>