Genotype distribution of enterovirus group C in Shandong Province, China / 病毒学报
Chinese Journal of Virology
;
(6): 363-367, 2010.
Artículo
en Chino
| WPRIM
| ID: wpr-286111
ABSTRACT
Human Enterovirus C group (HEV-C) includes 17 serotypes, which can not be serotype-identified by neutralization test using antiserum pool for NPEV. In order to elucidate the genotypes and molecular evolution of HEV-C in Shandong Province, We selected the strains isolated from AFP cases between 1994-2009 to perform reverse transcriptase-polymerase chain reactions (RT-PCR) by the primers specific for entire VP1 coding gene of HEV-C and sequencing. The phylogenetic tree was then constructed among these VP1 nucleotide sequences and other prototype strains. Totally 12 Shandong local strains were obtained and separated into 4 genotypes, CVA20, CVA21,CVA24 and EV 96. The homologous comparison and phylogenetic analysis showed Shandong strains were distinct from prototype strains in each genotype. This report showed that different genotype HEV-C strains spread widely in Shandong Province.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Filogenia
/
Datos de Secuencia Molecular
/
Línea Celular
/
China
/
Clasificación
/
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
/
Enterovirus Humano C
/
Genética
/
Genotipo
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
Chinese Journal of Virology
Año:
2010
Tipo del documento:
Artículo
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